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Blast or Fasta mn farq

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Asking AI: Clustal W

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Q. Hi mera thorra concept clear kr do clustal w k bare mn. dekho sb sy phle hum NCBI se kisi ek nucleotide ka sequence uthaingay phir usko blast run kreingay or phir wahan se sequence copy kr k clustal w pr paste krengay results check krne k liye. But hum ko ncbi se kitne sequence uthane hungay or hum blast q run kreingay? hum seedha clustal w pr q nhi jayngay? **ClustalW** ek aam taur par istemal hone wala multiple sequence alignment program hai, jo DNA ya protein sequences ko align karne mein madad karta hai. Iska istemal aksar bioinformatics research mein hota hai. Aapne sahi kaha ki hum NCBI se kisi ek nucleotide ka sequence utha sakte hain, phir usko **BLAST** run karke related sequences ko dhoond sakte hain, aur phir ClustalW mein un sequences ko align kar sakte hain. Lekin aapke sawalon ka jawab step-by-step: 1. **NCBI se Sequence Uthana**:     - NCBI (National Center for Biotechnology Information) se aap kisi bhi nucleotide ya protein sequence ko retrieve kar sakte hai...
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blast kese kam krta h?

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 **BLAST (Basic Local Alignment Search Tool)** ek powerful bioinformatics tool hai jo sequences ke beech mein similarity dhoondne mein madad karta hai. Chaliye main aapko BLAST ke kaam karne ka tareeka samjhaata hoon: 1. **Query Sequence Aur Target Sequence**:     - Har BLAST run mein ek **query sequence** hoti hai, jo aapke paas available hai. Yeh woh sequence hai jiske similarity ko hum dhoondna chahte hain.     - **Target sequence** ya **database** woh set of sequences hota hai jisse hum compare karte hain. Yeh database mein kai tarah ki sequences hote hain, jaise nucleotide sequences (blastn), protein sequences (blastp), ya unka combination (tblastx). 2. **Heuristic Approach**:     - BLAST ek **heuristic method** hai, matlab yeh dynamic programming algorithm hai jo tezi se kaam karta hai. Lekin iski sensitivity thodi kam hoti hai.     - Heuristic approach se BLAST database mein similarities dhoondta hai. Isse BLAST tezi se results deta ha...
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